Discovered by accident but thought many who like to complete games would appreciate the knowledge share.


Click 'Settings' and make these 2 changes.
Difficulty level: Easy
"Difference only" mode: Off


Select your level then click on the center screen to start the level.
The game should start paused with just a pixel pattern of bacteria.


On the left click on the single square.


Proceed to click each square on the center screen, pixel by pixel until the screen is completely empty. Meaning only a black screen remains in the center. Then click the middle right arrow.


The text at the bottom will read 'Level Solved! and include how many clicks.
See picture below.

Screenshot completing final monochrome level using this method and the achievement registering.


Back at the level select:

Whenever a doctor cannot do good, he must be kept from doing harm.

• Unlocked for me while playing through 'Play in color' and clicking frantically as bacteria reproduced. I suspect related to a specific level as other achievements, destroy x amount of bacteria or x amount of clicks maybe.
  
  
  • Asulith adds, I got 'it' completing color L01010.
    
  • SwAlL adds, I actually think that 'it' unlocks by completing level 10100
    
  • Kalinka adds, I got colors are the smiles of nature from completing color L01010
    
  • Rawphoric adds, also unlocked for me after completing L01010.
    
  • Maluno adds, when completed color L01010
    
  • MightyIrko adds, Also after completing color L01010 (same as Asulith)
    
    
  • Totouboros
    Uhm you wrote in colour achievements that one should just destroy the bacteria or so, but you actually have coloured cells (when you just start the level and let it play they will make formations and cycle through them endlessly) and those cells are "unstable" you just have to figure out how to make them destroy themselves (you can try stopping at certain formations/patterns and then clicking some of the blue cells away, the yellow ones will then jump around and if you clicked the right blue ones away the yellow ones will destroy the piece). With each level there are different unstable cells, in some levels there are also stable pieces made of solely blue cells, you don't have to destroy those.
    comment part 2: You only have to destroy the unstable patterns, and since each level has a different starting pattern with unstable cells, you gotta figure out each time which cells to remove so it can selfdestroy. I usually try to pause those coloured cells when there are few yellow ones and then destroy some interconnecting blue ones or make "arrows" with a yellow cell as point since those then also rather selfdestroy and destroy the rest of the piece too if you're lucky. I just thought i'll add this bit of info since frantically clicking around didn't work very efficiently lol.

Illness is the doctor to whom we pay most heed; to kindness, to knowledge, we make promise only; pain we obey.

• Unlocked for me while playing through 'Play in color' and clicking frantically as bacteria reproduced. I suspect related to a specific level as other achievements, destroy x amount of bacteria or x amount of clicks maybe.
  
  
  • SwAlL adds, he thinks it will unlock in a level before the above.
    
  • Rawphoric adds, unlocked for me after completing L10100.
    
  • Maluno adds, when completed color L10100
    
  • MightyIrko adds, Got it at color 10100 without clicking much (I used only two points so it doesnt have to do much with clicking)

Doctors are great - as long as you don't need them.

• 'Play in color', beat level L11111 (binary for 31)
  

A doctor gave a man six months to live. The man couldn't pay his bill, so he gave him another six months.

• 'Play in monochrome', beat level L01111 (binary for 15)
  
  

The life so short, the craft so long to learn.

• 'Play in monochrome', beat level L11111 (binary for 31)
  

There is no such thing as an infallible doctor.

• Click 'Simulation mode' on the main screen.
  

6/9
• Added info provided by Asulith. Thanks!

5/28
• Organized with sections instead of headers.
  
• Added info provided by SwAlL. Thanks!